kanamycin kinase | |||||||
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Identifiers | |||||||
EC number | 2.7.1.95 | ||||||
CAS number | 62213-36-9 | ||||||
Databases | |||||||
IntEnz | IntEnz view | ||||||
BRENDA | BRENDA entry | ||||||
ExPASy | NiceZyme view | ||||||
KEGG | KEGG entry | ||||||
MetaCyc | metabolic pathway | ||||||
PRIAM | profile | ||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||
Gene Ontology | AmiGO / EGO | ||||||
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In enzymology, a kanamycin kinase (EC 2.7.1.95) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are ATP and kanamycin, whereas its two products are ADP and kanamycin 3'-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:kanamycin 3'-O-phosphotransferase. This enzyme is also called neomycin-kanamycin phosphotransferase.
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1J7I, 1J7L, 1J7U, 1L8T, 1ND4, 2B0Q, and 2BKK.